| ISBN: | 9780197583746 |
| 语种代码: | eng |
| 个人名称: | Cooper, Geoffrey M., |
| 题名: | The cell : a molecular approach / Geoffrey M. Cooper, Kenneth W. Adams. |
| 版本说明: | International ninth edition. |
| 出版发行项: | New York, NY : Oxford University Press, [2023] |
| 载体形态: | xxvii, 788 pages ; illustrations (chiefly color) ; 28 cm |
| 书目附注: | Includes bibliographical references (pages 749-752) and index. |
| 格式化内容附注: | Part 1. Fundamentals and Foundations -- Part 2. The Flow of Genetic Information -- Part 3. Subcellular Structures and Functions -- Part 4. Cell Regulation. |
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| 格式化内容附注: | Introduction to Cells and Cell Research. The origin and evolution of cells ; Experimental models in cell biology ; Tools of cell biology: Microscopy and subcellular fractionation -- Physical Principles Underlying Cell Structure and Function. Chemical bonds, thermodynamics, and ATP ; Organic molecules of cells ; Enzymes as biological catalysts ; Cell membranes -- Fundamentals of Molecular Biology. Heredity, genes, and DNA ; Expression of genetic information ; Recombinant DNA technology ; Techniques to detect and examine nucleic acids and proteins ; Techniques to study gene function in eukaryotes -- Genes and Genomes. The structure of eukaryotic genes ; Noncoding sequences ; Chromosomes and chromatin -- Replication, Maintenance, and Rearrangements of Genomic DNA. DNA replication ; DNA repair ; DNA rearrangements and gene amplification -- RNA Synthesis and Processing. Transcription in bacteria ; Transcription in eukaryotes ; RNA processing and turnover -- Transcriptional Regulation and Epigenetics. Gene regulation in E. coli ; Transcription factors in eukaryotes ; Chromatin and epigenetics -- Protein Synthesis, Processing, and Regulation. Translation of mRNA ; Protein folding and processing ; Regulation of protein function and stability -- Genomics, Proteomics, and Systems Biology. Genomics and transcriptomics ; Proteomics ; Systems biology -- The Nucleus. The nuclear envelope and traffic between the nucleus and the cytoplasm ; The organization of chromatin ; Nuclear bodies -- |
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| 格式化内容附注: | Protein Processing and Sorting: The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes. The endoplasmic reticulum ; The Golgi apparatus ; The mechanism of vesicular transport ; Lysosomes -- Mitochondria, Chloroplasts and Peroxisomes. Mitochondrial structure, composition, and dynamics ; Oxidative catabolism of glucose and fatty acids ; Oxidative phosphorylation ; Mitochondrial assembly and maintenance ; Chloroplasts and other plastids ; Peroxisomes -- The Cytoskeleton and Cell Movement. Structure and organization of actin filaments ; Myosin motors ; Microtubules ; Microtubule motors and movement ; Intermediate filaments -- The Plasma Membrane. Structure of the plasma membrane ; Transport of small molecules ; Internalization of large molecules by endocytosis -- Cell Walls, the Extracellular Matrix and Cell Interactions. Cell walls ; The extracellular matrix and cell-matrix interactions ; Cell-cell interactions -- Cell Signaling. Signaling molecules and their receptors ; G proteins and cyclic AMP ; Tyrosine kinases and signaling by the MAP kinase and PI 3-kinase pathways ; Receptors coupled to transcription factors ; Signaling dynamics and networks -- The Cell Cycle. The eukaryotic cell cycle ; Regulators of cell cycle progression ; The events of M phase -- Cell Renewal and Cell Death. Stem cells and the maintenance of adult tissues ; Pluripotent stem cells, cellular reprogramming, and regenerative medicine ; Programmed cell death -- Cancer. The development and causes of cancer ; Oncogenes ; Tumor suppressor genes ; Molecular approaches to cancer treatment -- Appendix -- Answers -- Glossary. |